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Eosinophilic oesophagitis is a chronic inflammatory condition that afflicts children and adults, and causes oesophageal narrowing and fibrosis, with the resultant clinical sequelae of dysphagia and food bolus obstruction events, the latter often resulting is hospitalisation, emergency endoscopic removal and rarely but catastrophically oesophageal perforation

Scholarcy highlights

  • Eosinophilic oesophagitis is a chronic inflammatory condition that afflicts children and adults, and causes oesophageal narrowing and fibrosis, with the resultant clinical sequelae of dysphagia and food bolus obstruction events, the latter often resulting is hospitalisation, emergency endoscopic removal and rarely but catastrophically oesophageal perforation
  • An increasing number of patients are being diagnosed with EoE, and this is independent of a growing awareness of this recently defined condition, but rather represents a true increase in the context of a global rise of allergic conditions per se
  • A role for aeroallergens and dietary allergens in precipitating or causing EoE has been suggested in a number of studies, albeit limited by their retrospective nature and lack of control group, the predominance of paediatric literature and variable use of adjunctive treatment such as proton pump inhibitors
  • The need both to better understand the role of food and aeroallergens, and to offer less invasive and thereby safer endoscopic surveillance is readily apparent

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