Melatonin, aging, and COVID-19: Could melatonin be beneficial for COVID-19 treatment in the elderly?

The aim of this review is to summarize current studies on the relationship between melatonin and aging

Güler ÖZTÜRK; Kazime Gonca AKBULUT; Şevin GÜNEY


Scholarcy highlights

  • During the aging process, the cell's ability to cope with external and internal stress and its functional capacity is diminished by time
  • Increased free radical levels in tissues during aging processes have been reported by several studies
  • Melatonin is a rather powerful and effective endogenous radical scavenger, and attenuates increased oxidative stress caused by several toxic substances like safrole and paraquat in tissues
  • Melatonin plays an important role in many processes in the body, especially in healthy aging and prevention of free-radical-related diseases
  • The decrease in melatonin production and altered melatonin rhythms with aging can lead to an inhibited immune system
  • The use of melatonin as an antiviral immunostimulant should be supported by studies

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