We have reviewed studies focused on nutrient effects on auditory function
2018
Key concepts
- Hearing loss
- University of Wisconsin
- animal model
- United States of America
- reactive oxygen species
- methylmalonic acid
- noise induced hearing loss
- environmental factor
- docosahexaenoic acid
- dietary restriction
- Healthy Eating Index
- World Health Organization
- isocitrate dehydrogenase 2
- presbycusis
- thymidylate synthase
- eicosapentaenoic acid
- methylenetetrahydrofolate reductase
- vitamins
- proteins
- folic acid
- caloric restriction
Scholarcy highlights
- Hearing loss is a common disorder that has multifactorial origin, including both genetic and environmental factors
- This study demonstrated that higher intakes of vitamin A and E resulted in an inverse association with the prevalence of HL, it was not possible to demonstrate a reduction of the HL prevalence due to the intake of antioxidant combinations as shown in animal models
- This study presented association of high vitamin D serum concentrations and worse auditory function, a result that was in agreement with previous works that showed that vitamin D-deficient diets prevent age-related HL in a mouse model and that chronic sun exposure in the elderly could be a risk factor for HL
- Caloric restriction may be an interesting option to avoid HL, as suggested by results obtained in animal models, but extensive human studies are needed to verify this possibility
- Vitamins A and folic acid, as well as minerals such as iodine may offer an alternative to improve HL in a population at risk by slowing down the progression of the disorder as deduced from the available studies carried to date
- Its incidence varies in each population segment, affecting approximately 10% of children and increasing to 30% of the population over 65 years
- Data derived specially from animal models have revealed the importance of the genetic background in the outcomes obtained from different dietary patterns and some associations to single nucleotide polymorphisms are emerging in addition to the well-known role of connections in hearing impairments
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