We have reviewed studies focused on nutrient effects on auditory function
2018
Key concepts
- docosahexaenoic acid
- methylmalonic acid
- University of Wisconsin
- environmental factor
- dietary restriction
- eicosapentaenoic acid
- methylenetetrahydrofolate reductase
- animal model
- thymidylate synthase
- proteins
- reactive oxygen species
- isocitrate dehydrogenase 2
- World Health Organization
- Healthy Eating Index
- presbycusis
- noise induced hearing loss
- folic acid
- vitamins
- United States of America
- caloric restriction
- Hearing loss
Scholarcy highlights
- Hearing loss is a common disorder that has multifactorial origin, including both genetic and environmental factors
- This study demonstrated that higher intakes of vitamin A and E resulted in an inverse association with the prevalence of HL, it was not possible to demonstrate a reduction of the HL prevalence due to the intake of antioxidant combinations as shown in animal models
- This study presented association of high vitamin D serum concentrations and worse auditory function, a result that was in agreement with previous works that showed that vitamin D-deficient diets prevent age-related HL in a mouse model and that chronic sun exposure in the elderly could be a risk factor for HL
- Caloric restriction may be an interesting option to avoid HL, as suggested by results obtained in animal models, but extensive human studies are needed to verify this possibility
- Vitamins A and folic acid, as well as minerals such as iodine may offer an alternative to improve HL in a population at risk by slowing down the progression of the disorder as deduced from the available studies carried to date
- Torre et al evaluated the effect of CR in ARHL comparing monkeys fed a low fat, high fiber diet ad libitum with others fed a 30% lower amount of the same diet
- Data derived specially from animal models have revealed the importance of the genetic background in the outcomes obtained from different dietary patterns and some associations to single nucleotide polymorphisms are emerging in addition to the well-known role of connections in hearing impairments
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