Investigation of the Immune Modulatory Potential of Zinc Oxide Nanoparticles in Human Lymphocytes

Nanotechnology is a rapidly evolving field and is considered one of the key technologies of the 21st century

Helena Moratin; Pascal Ickrath; Agmal Scherzad; Till Jasper Meyer; Sebastian Naczenski; Rudolf Hagen; Stephan Hackenberg

2021

Scholarcy highlights

  • Nanotechnology is a rapidly evolving field and is considered one of the key technologies of the 21st century
  • The Zinc oxide nanoparticles used in this study were spherical in shape with a mean diameter of
  • Data were obtained in one exemplary experiment
  • The particles used for these experiments did not induce any significant in vitro
  • The particles used for these experiments did not induce any significant alterations alterations in cell activation markers of lymphocytes, and the composition of T cell subin cell activation markers of lymphocytes, and the composition of T cell subpopulations populations remained stable
  • The use of nanoparticles for the production of consumer products has products has increased over many years, and a variety of different routes exist for a direct increased over many years, and a variety of different routes exist for a direct entry of NP
  • The performance of confocal imaging or transmission electron microscopy to investigate particle uptake and cellular responses at different time points of incubation with NP would be a challenging but interesting approach to further improve knowledge of the immune modulating potential of NP

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