Functionalization of Metal and Carbon Nanoparticles with Potential in Cancer Theranostics

We summarize and compare the most promising metal- and carbon-based theranostic tools reported as potential candidates in precision cancer theranostics

Nicolò Mauro

Scholarcy highlights

  • Cancer theranostics is an emerging field of nanotechnology that combines therapy and diagnosis in a single smart tool, providing real-time monitoring of treatment progress and efficacy
  • Among the most promising theranostic tools proposed in recent literature panorama, gold nanoparticles, superparamagnetic iron oxide nanoparticles, carbon nanodots and graphene oxide have shown intriguing characteristics exploitable in biomedicine and especially in cancer theranostics
  • Recent works have shown that well-designed nanosystems with tunable interfacial, physical-chemical and optical features could be obtained in order to display multimodal imaging and selective non-invasive eradication of tumors
  • Each type of nanosystem seems to have some characteristic advantage, but it might be noticed that better results could be obtained by designing multimodal nanohybrid “machines” capable in a single platform of imaging, monitoring and sensing tumors while treating cancer cells
  • Hybrid nanotheranostics represent the future of personalized cancer treatments and require more in-depth knowledge of basic information about tissue/nanomaterial interactions to develop safe nanomedicines
  • Further efforts should be made to design smart nanomaterials with well-established architectures using highly tunable, industrially scalable and cost-effective synthetic routes to overcome the existing regulatory barriers that have limited their translation into the clinic

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