Selectivity in the Reinnervation of the Lateral Gastrocnemius Muscle after Nerve Repair with Ethyl Cyanoacrylate in the Rat

This study demonstrates that the precision in reinnervation of the lateral gastrocnemius muscle is far from perfect after repair with ethyl cyanoacrylate

Thomas Landegren

2011

Scholarcy highlights

  • Experimental and clinical results of neural anastomosis using microsutures have been shown to be less than satisfactory in adults
  • The repair technique using interrupted nylon microsutures is currently accepted as the golden standard of peripheral nerve repair
  • To improve the functional outcome of peripheral nerve repair, a sutureless seam with synthetic adhesive has been proposed as an option to microsutures for achieving proper coaptation of the nerve endings
  • QUANTITATIVE AND DESCRIPTIVE ESTIMATIONS OF RETROGRADELY LABELED MOTONEURON To investigate the anatomical distribution of α-MNs innervating the lateral gastrocnemius muscle in the lateral ventral horn of the spinal cord, micrographs from every five of all serially cut 14-μm sections from the L5 spinal cord segment were transformed into separate layers using Adobe Photoshop 7.0
  • This study demonstrates that the precision in reinnervation of the LGC is far from perfect after repair with ethyl cyanoacrylate
  • The limited number of animals used in this study shows a tendency to greater labeling of anterior horn cells from the LGC when synthetic adhesives are used, but this finding does not reach statistical significance
  • From a speculative point of view, that this avenue will prove to be fruitful in distinguishing the relative values of immediate and late repair of peripheral nerves

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