Epigenetic Regulation of Matrix Metalloproteinase-1 and -3 Expression in Mycobacterium tuberculosis Infection

We investigated the role of changes in histone acetylation in Mycobacterium tuberculosis -induced Matrix metalloproteinase expression using inhibitors of histone deacetylases and histone acetyltransferases, HDAC siRNA, promoter-reporter constructs, and chromatin immunoprecipitation assays

Rachel C. Moores; Sara Brilha; Frans Schutgens; Paul T. Elkington; Jon S. Friedland


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