Combining Cellulose and Cyclodextrins: Fascinating Designs for Materials and Pharmaceutics

This review focuses on the key advances in developing materials based on these conjugates

Tânia F. Cova


Scholarcy highlights

  • Cyclodextrins and cellulose are fascinating molecules with synergistic properties that have been critical for preparing new derivatives directed at several innovative applications, ranging from textiles coatings, sensors and paper making to pharmaceutical technology
  • These combine the favorable properties of cellulose adsorption and wettability with the capacity of CDs to form inclusion complexes with a wide range of guest molecules, including hydrocarbon amphiphiles and drugs. In this type of structures, CDs can be covalently attached to the surface of cellulose so that the cavity of the former is accessible to the guest molecules
  • The dyeing process can be carried out using a different methodology, in which a host-guest compound is initially formed between the dye and a cyclodextrin and, the supramolecular complex is bound to the cotton surface
  • Considering the higher selectivity of the CD cavity toward adamantine, the latter is grafted to carboxymethyl cellulose allowing the formation of a layer on the modified Au-NPs
  • The design of advanced materials based on cellulose and cyclodextrin derivatives is still a challenging and ingenious proving-ground, from both the academic and commercial points of view
  • Several approaches are currently introduced to produce cellulose derivatives with improved properties that can be applied in different scenarios
  • This means that substantial efforts involving chemical-physics, synthetic organic chemistry, must be combined with work on materials design and characterization, and drug delivery for obtaining products that make a change

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