The pathogenesis of atopic dermatitis

Atopic dermatitis is a chronic inflammatory skin disease, clinically and histologically very similar to contact dermatitis

2020

Scholarcy highlights

  • Atopic dermatitis is a chronic inflammatory skin disease, clinically and histologically very similar to contact dermatitis
  • The skin is much more than just a protective coat and encounters a high number of antigens at the interface between the body and the surrounding environment
  • AD can occur at any age and has a high prevalence in children
  • The rising interest in this disease has been forced by its increasing prevalence in Western societies and its contribution to the worsening of health care costs
  • Cardinal features of AD are erythematous eczematous skin lesions, flexural lichenifications or papules which go along with an intense pruritus and cutaneous hyperreactivity.56. Various names, such as atopic eczema, neurodermitis constitutionalis, endogenous eczema, eczema flexurarum, Besnier’s prurigo, asthma eczema, or hay fever eczema have been created for this disease and indicate that still no precise clinical definition of AD exists
  • The exact pathophysiosiological mechanisms leading to AD are still elusive and various studies have tried to unravel the key factors leading to this disease

Need more features? Save interactive summary cards to your Scholarcy Library.