Advances in Novel Drug Delivery Strategies for Breast Cancer Therapy

This paper provides an overview of breast cancer, conventional therapy, potential of nanotechnology in management of breast cancer, and rational approaches for targeting breast cancer

Ritu Dhankhar

2010

Scholarcy highlights

  • Breast cancer remains one of the world's most devastating diseases with more than 7,600,000 deaths and 1,301,867 new cases every year
  • Nanotechnology offers opportunities to achieve drug targeting with newly discovered breast-cancer-specific targets
  • Effective targeting would require a better understanding of the target and a development of the targeting system
  • Nanotechnology provides a number of distinct nanocarriers, which vary with respect to many properties, such as particle size, shape, charge, and surface modification
  • Nanocarriers enable the solubilization of poorly soluble anticancer drugs and increasing their bio-availability
  • Over the past decade tremendous progress has been made in the elucidation of molecular signalling pathways and their ligands in breast cancer
  • The growing field of nanotechnology in combination with advanced molecular biology of cell signaling pathways may make possible the development of an entire new generation of specific therapy for breast cancer

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