Preparation of Poly(D,L-Lactide/Glycolide) Nanoparticles of Controlled Particle Size Distribution: Application of Experimental Designs

This study investigates the use of the solvent evaporation method for preparing acid

M. C. Julienne

2007

Scholarcy highlights

  • This study investigates the use of the solvent evaporation method for preparing acid
  • a high pressure homogenizer to reduce the droplet size of the emulsion initially formed
  • a composite rotational experimental design was employed to evaluate the joint influence of three formulation variables on the micromeritic properties
  • Analysis of variance corresponding to the experimental design
  • whereas the polydispersity is affected by the homogenization pressure
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