Biologically active secondary metabolites from Actinomycetes

This review demonstrates the diversity of secondary metabolites produced by actinomycete strains with respect to their chemical structure, biological activity and origin

Jolanta Solecka; Joanna Zajko; Magdalena Postek; Aleksandra Rajnisz

2012

Scholarcy highlights

  • Secondary metabolites obtained from Actinomycetales provide a potential source of many novel compounds with antibacterial, antitumour, antifungal, antiviral, antiparasitic and other properties
  • The majority of these compounds are widely used as medicines for combating multidrug-resistant Gram-positive and Gram-negative bacterial strains
  • Actinomycetes have been isolated from terrestrial soils, from the rhizospheres of plant roots, and recently from marine sediments
  • This review demonstrates the diversity of secondary metabolites produced by actinomycete strains with respect to their chemical structure, biological activity and origin
  • On the basis of this diversity, this review concludes that the discovery of new bioactive compounds will continue to pose a great challenge for scientists

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