Impact of nanoparticles on neuron biology: current research trends

This review provides a bird’s eye view approach on the effects of various nanoparticles on neuronal differentiation, neuronal survivability, neuronal growth, neuronal cell adhesion, and functional and behavioral recovery

Firdos Khan

2018

Scholarcy highlights

  • Introduction of nanoparticlesNanoparticles or nanomaterials are one millionth of a millimeter, ~100,000 times smaller than the diameter of a human hair
  • Over the past few years, synthetically derived nanoparticles generated tremendous interests and based on the chemical compositions, nanoparticles can be broadly classified into two major classes such as organic materials, which are liposomes, dendrimers, carbon nanotubes, emulsions, and other polymers, and inorganic materials, which include metals
  • Research has shown that many nanoparticles promoted neuronal differentiation and enhanced neuronal survival and neuronal growth and maturation
  • Sometimes one nanoparticle is conjugated with another nanoparticle or biomolecules to enhance the effects
  • The researchers must know the size of nanoparticles before testing them for anticipated response
  • It would be interesting to study the molecular mechanism of the nanoparticle action on neurons

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