Innate and adaptive immunity in teleost fish: a review

The aim of this review is to provide a review of the immune system in fish, including the ontogeny, mechanisms of unspecific and acquired immunity and the action of some immunomodulators

C. Uribe; H. Folch; R. Enriquez; G. Moran


Scholarcy highlights

  • The immune system of fish is physiologically similar to that of higher vertebrates, despite certain differences
  • The aim of this review is to provide some background on the immune system of fish, describing the ontogeny and core components, the nonspecific and adaptive immune mechanisms and elements that promote their actions as immunomodulators
  • Great progress has been made in understanding the immune response of fish which has benefitted the growing aquaculture industry worldwide
  • The production of fish larvae is often hampered by high mortality rates and economic loss due to infectious diseases
  • The immunomodulation of larval fish has been proposed as a potential method for improving larval survival by increasing the innate responses of developing animals until their adaptive immune response is sufficiently developed to mount an effective response to the pathogen
  • This is a crucial point in further research that is currently focused on increasing the survival of larval fish
  • Dalmo suggest that the development of strategies to control pathogen load and immuno-prophylactic measures must be implemented further to realise the full potential of the production of marine fish larvae and improve the overall production of adult fish

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