Concentrations of polychlorinated biphenyls, hydroxylated metabolites of PCBs and octachlorostyrene, and pentachlorophenol were determined in umbilical cord plasma samples from three different regions of Québec
2010
Pentachlorophenol and hydroxylated polychlorinated biphenyl metabolites in umbilical cord plasma of neonates from coastal populations in Québec.
Key concepts
Scholarcy highlights
- Concentrations of polychlorinated biphenyls, hydroxylated metabolites of PCBs and octachlorostyrene, and pentachlorophenol were determined in umbilical cord plasma samples from three different regions of Québec
- In Nunavik and Lower North Shore samples, free thyroxine concentrations were negatively correlated with the sum of quantitated chlorinated phenolic compounds and were not correlated with any PCB congeners or sigma PCBs. This suggests that PCP and HO-PCBs are possibly altering thyroid hormone status in newborns, which could lead to neurodevelopmental effects in infants
- Further studies are needed to examine the effects of chlorinated phenolic compounds on thyroid hormone status in newborns
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