APOE genotype influences acquisition and recall following traumatic brain injury

APOE has been demonstrated to influence traumatic brain injury outcome

F. C. Crawford; R. D. Vanderploeg; M. J. Freeman; S. Singh; M. Waisman; L. Michaels; L. Abdullah; D. Warden; R. Lipsky; A. Salazar; M. J. Mullan

2012

Scholarcy highlights

  • APOE has been demonstrated to influence traumatic brain injury outcome
  • The relationship between APOE genotype and memory following TBI was examined in 110 participants in the Defense and Veterans’ Head Injury Program
  • Memory performance was worse in those who had an APOE ε4 allele than those who did not, whereas genotype groups did not differ on demographic or injury variables or on measures of executive functioning. These data support a specific role for the APOE protein in memory outcome following TBI, and suggest an APOE isoform–specific effect on neuronal repair processes
  • If you are uploading a letter concerning an article: You must have updated your disclosures within six months: http://submit.neurology.org
  • I, the first and corresponding author, verify that I have read the contents of the PUBLISHING AGREEMENT form. *
  • NOTE: All authors, besides the first/corresponding author, must complete a separate Publishing Agreement Form and provide via email to the editorial office before comments can be posted

Need more features? Save interactive summary cards to your Scholarcy Library.