To evaluate whether T3 analogs would have a differential effect on TR beta 1 and TR beta 1 mutants and be a specific treatment for patients with resistance to thyroid hormone, we examined the induction of the transcriptional activation of wild-type TR alpha 1, TR beta 1, and mutant TR beta 1s by T3, Triiodothyroacetic acid, and triiodothyropropionic acid
2014