We provide a short history of the discovery of the lipocortin family, establish their relationship to other previously described calcium phospholipid-binding proteins, and reviews what is known about six members of this family
2020
Key concepts
Scholarcy highlights
- We provide a short history of the discovery of the lipocortin family, establish their relationship to other previously described calcium phospholipid-binding proteins, and reviews what is known about six members of this family
- Lipocortins were first discovered as potential mediators of steroid action
- Anti-inflammatory steroids inhibit the production of eicosanoids by inhibiting the release of arachidonic acid
- The epidermal growth factor receptor is a membrane-associated protein tyrosine kinase, which when activated through the binding of epidermal growth factor, phosphorylates cellular proteins that may have important roles in growth regulation
- The discovery of the lipocortin family of calcium phospholipid-binding proteins has established an important link in the signal transduction process
Need more features? Save interactive summary cards to your Scholarcy Library.