Cattle tick vaccine researchers join forces in CATVAC

A meeting sponsored by the Bill & Melinda Gates Foundation was held at the Avanti Hotel, Mohammedia, Morocco, July 14–15, 2015

Theo Schetters; Richard Bishop; Michael Crampton; Petr Kopáček; Alicja Lew-Tabor; Christine Maritz-Olivier; Robert Miller; Juan Mosqueda; Joaquín Patarroyo; Manuel Rodriguez-Valle; Glen A. Scoles; José de la Fuente

2016

Scholarcy highlights

  • A meeting sponsored by the Bill & Melinda Gates Foundation was held at the Avanti Hotel, Mohammedia, Morocco, July 14–15, 2015
  • These efforts have met with some success in cattle tick vaccine research, but none of the vaccines appeared effective enough to sufficiently control tick infestation or transmission of the pathogens carried by them
  • In order to establish a closer collaboration between research groups that work on tick vaccines, a two-day meeting sponsored by the Bill & Melinda Gates Foundation was held on July 14-15th, 2015 at the Avanti Hotel in Mohammedia, Morocco
  • At the meeting it was decided to establish a formal collaboration among the groups to facilitate exchange of antigens and evaluation of candidate vaccine formulations in standardized experimental models. This collaboration resulted in the formation of the Cattle Tick Vaccine Consortium
  • Cattle that were vaccinated with 100 μg of Bm86 produced in P. pastoris and 50 μg of SUB produced in E. coli in separate vaccine formulations in Montanide ISA 50 V2 adjuvant were almost completely protected against R. microplus infestation
  • In order to improve clarity about efficacy of tick vaccines, especially the way this is communicated in abstracts of scientific publications that are published on line, it was decided to always present the percentage reduction in the number of engorged females upon infestation with R. microplus larvae
  • TS, RB, MC, PK, ALT, CMO, RM, JM, JP, MRV, GAS and JF participated in the meeting and contributed to the update on the tick vaccine research and selection and evaluation of possible combinations of tick antigens that hold promise as an effective vaccine against cattle ticks, R. microplus using standardized experimental models

Need more features? Save interactive summary cards to your Scholarcy Library.