This paper presents an alternative method for studying biological cells using a BioimprintTM technique with atomic force microscope analysis, to enable the high-resolution replication and imaging of the surface topography of human endometrial cancer cells

JJ Muys

2006

Scholarcy highlights

  • Optical microscopy techniques are the primary method for cell surface visualization, with microscopic characteristics of cells traditionally used for diagnosis and classification of cancers
  • This paper presents an alternative method for studying biological cells using a BioimprintTM technique with atomic force microscope analysis, to enable the high-resolution replication and imaging of the surface topography of human endometrial cancer cells
  • BioimprintTM overcomes many of the inherent difficulties associated with cellular imaging by AFM and advances their integration as investigative tools in biology
  • It is difficult to deduce if the varying shapes and forms are potential characteristics linked to malignant cell mutations, or if they are artifacts induced from the BioimprintTM replication process
  • This study reports preliminary work in the areas of cellular replication and endometrial cancer cell imaging by atomic force microscopy

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