Multimodal management of malignant pleural mesothelioma: where are we today?

Malignant pleural mesothelioma is an uncommon tumour arising from the parietal pleura and is characterised by a peculiar growth pattern extending along the pleural surface from the costodiaphragmatic sinus, where frequently a large amount of tumour is found, to the apical region of the chest

P. E. Van Schil

2014

Scholarcy highlights

  • Malignant pleural mesothelioma is an uncommon tumour arising from the parietal pleura and is characterised by a peculiar growth pattern extending along the pleural surface from the costodiaphragmatic sinus, where frequently a large amount of tumour is found, to the apical region of the chest
  • Surgery with curative intent To remove as much tumour as possible, different surgical procedures exist in order to obtain a macroscopic complete resection or maximal debulking with the intent to improve local control and prolong disease-free survival
  • The role of extensive surgical treatment is currently redefined in mesothelioma patients and no definite guidelines can yet be provided
  • Every patient with suspicion of mesothelioma should be discussed by a multidisciplinary tumour board to provide a tailored diagnostic and therapeutic plan
  • More attention should be paid to quality control and selection criteria of multimodality treatment comprising extensive surgical procedures

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