The effect of in situ/in vitro three-dimensional quantitative computed tomography image voxel size on the finite element model of human vertebral cancellous bone

This study showed that there is a significant effect of the quantitative computed tomography image voxel size on FEcalculated apparent modulus and yield strength, which is in agreement with previous publications.16–18

Yongtao Lu

2014

Scholarcy highlights

  • Different clinical CT scan protocols are currently available for scanning human vertebrae, and quantitative computed tomography-based finite element models are generated from image datasets with different voxel sizes
  • First it is shown that the QCT image voxel size had no effect on the apparent bone mineral density
  • Within each in situ/in vitro comparison pair, the datasets were acquired with the same tube voltage, which is a factor influencing the CT values and the BMD
  • This study showed that there is a significant effect of the QCT image voxel size on FEcalculated apparent modulus and yield strength, which is in agreement with previous publications
  • To the authors’ knowledge, the study performed in this article was the first to investigate the influence of QCT voxel size on the FE models at the clinical resolution level, only high-resolution QCT images were investigated
  • The authors would like to acknowledge the Department of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, for providing the in situ quantitative computed tomography image datasets; Dr Peter Varga for some technical supports and Miss Imke Fiedler for assisting in the bone mineral density and finite element calculations

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