Prediction of Creatinine Clearance from Serum Creatinine

A formula has been developed to predict creatinine clearance from serum creatinine in adult males: Ccr = /72 × Scr(mg/100ml)

Donald W. Cockcroft; Henry Gault

2008

Scholarcy highlights

  • A formula has been developed to predict creatinine clearance from serum creatinine in adult males: Ccr =/72 × Scr(mg/100ml)
  • Derivation included the relationship found between age and 24-hour creatinine excretion/kg in 249 patients aged 18–92
  • Values for Ccr were predicted by this formula and four other methods and the results compared with the means of two 24-hour Ccr’s measured in 236 patients
  • Factors for age and body weight must be included for reasonable prediction

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