Human mitochondrial NADP-dependent isocitrate dehydrogenase in man-mouse somatic cell hybrids

Human mitochondrial NADP-dependent isocitrate dehydrogenase is expressed in man-mouse somatic cell hybrids as a dimeric molecule. The gene specifing this enzyme was observed to be syntenic with the mannose phosphate isomerase locus in the 56 primary man-mouse clones in this series

G.A.P. Bruns; R.E. Eisenman; P.S. Gerald

2008

Key concepts

Scholarcy highlights

  • Human mitochondrial NADP-dependent isocitrate dehydrogenase is expressed in man-mouse somatic cell hybrids as a dimeric molecule. The gene specifing this enzyme was observed to be syntenic with the mannose phosphate isomerase locus in the 56 primary man-mouse clones in this series
  • The human IDH-2 locus, may be assigned to chromosome 15

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