Acupuncture Treatment for Symptom Management in Atopic Dermatitis: A Study Protocol for a Randomized, Participant- and Assessor-Blind, Sham-Controlled Trial

We found a positive relationship between the severity of Atopic dermatitis symptoms and gastrointestinal symptoms such as epigastric tenderness and dyspepsia

Jung Gun Park; Hi-Joon Park; Younbyoung Chae; Yu-Kang Kim; Hyangsook Lee; Kyuseok Kim


Scholarcy highlights

  • Atopic dermatitis is a chronic inflammatory skin disease characterized by intense itching, skin dryness, erythema, exudate, crust, and lichenification
  • The incidence of AD is increasing in developed countries, and the disorder affects both children and adults
  • Acupuncture treatment has been performed in AD patients, but controlled clinical trials to assess its effectiveness are lacking
  • In our pilot study, acupuncture was shown to be more effective in relieving the symptoms of AD than sham acupuncture, and the severity of AD was associated with the presence of GI symptoms
  • The relationships between skin, brain, and GI system health and between AD and the central nervous system suggest a role for acupuncture in relieving the symptoms of interrelated disorders of these organ systems
  • There is a battery of outcome measures in this study. They can be divided into five categories: measures of the severity of AD symptoms: Scoring Atopic Dermatitis, Visual Analog Scale, VAS, Eczema Area and Severity Index, and Patient Oriented Eczema Measure, a measure of the quality of life affected by AD: Dermatology Life Quality Index, measures of the severity of dyspepsia symptoms: Nepean Dyspepsia Index-K, AR, VAS of dyspepsia, and abdominal Pressure Pain Threshold, measures of central nervous system responses of AD patients: EEG, and a credibility test, blinding test, and assessment of adverse effects
  • This study protocol will provide an important and thorough assessment of the effectiveness of twice-weekly acupuncture treatment in improving the symptoms of mildto-moderate Atopic dermatitis in adults

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