Manipulating Cellular Energetics to Slow Aging of Tissues and Organs

In this review we focus on the molecular mechanisms of the effect of physical exercise on muscle tissues

S. S. Sokolov; F. F. Severin

2020

Scholarcy highlights

  • Up to now numerous studies in the field of gerontology have been published
  • Physical activity is a well-documented anti-aging intervention being especially efficient in slowing down the age-associated decline of skeletal muscle mass
  • In this review we focus on the molecular mechanisms of the effect of physical exercise on muscle tissues
  • It is believed that the decline of both antioxidant and proliferative potentials of the cells causes the age-dependent decline of multiple tissues, rather than only the muscular one
  • We argue that the approach above is applicable for the majority of tissues in an organism

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