Demethylation-Induced Developmental Pleiotropy in Arabidopsis

The function of DNA methylation in higher plants was investigated by expression of a complementary DNA encoding a cytosine methyltransferase from Arabidopsis thaliana as an antisense RNA in transgenic plants

Michael J. Ronemus; Massimo Galbiati; Christine Ticknor; Jychian Chen; Stephen L. Dellaporta

2006

Scholarcy highlights

  • The function of DNA methylation in higher plants was investigated by expression of a complementary DNA encoding a cytosine methyltransferase from Arabidopsis thaliana as an antisense RNA in transgenic plants
  • Loss of methylation was observed in both repetitive DNA and single-copy gene sequences
  • These findings implicate DNA methylation in establishing or maintaining epigenetic developmental states in the meristem

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