Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray

A high-capacity system was developed to monitor the expression of many genes in parallel

Mark Schena; Dari Shalon; Ronald W. Davis; Patrick O. Brown

2006

Scholarcy highlights

  • A high-capacity system was developed to monitor the expression of many genes in parallel
  • Microarrays prepared by high-speed robotic printing of complementary DNAs
  • on glass were used for quantitative expression measurements of the corresponding genes
  • hybridization volumes of 2 microliters could be used that enabled detection of rare transcripts
  • in probe mixtures derived from 2 micrograms of total cellular messenger RNA
  • SCHENA M, STRUCTURE OF HOMEOBOX-LEUCINE ZIPPER GENES SUGGESTS A MODEL FOR THE EVOLUTION OF GENE FAMILIES, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA91, 8393

Need more features? Save interactive summary cards to your Scholarcy Library.