Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

Four persons developed marked parkinsonism after using an illicit drug intravenously

J. William Langston; Philip Ballard; James W. Tetrud; Ian Irwin

2006

Scholarcy highlights

  • Four persons developed marked parkinsonism after using an illicit drug intravenously
  • On the basis of the striking parkinsonian features observed in our patients, and additional pathological data from one previously reported case, it is proposed that this chemical selectively damages cells in the substantia nigra

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