Cofactor-containing peptide has been obtained in high yield from bovine serum amine oxidase
2006
A new redox cofactor in eukaryotic enzymes: 6-hydroxydopa at the active site of bovine serum amine oxidase
Key concepts
Scholarcy highlights
- Cofactor-containing peptide has been obtained in high yield from bovine serum amine oxidase
- Analysis of the peptide by mass spectrometry, ultraviolet-visible spectroscopy, and proton nuclear magnetic resonance leads to the identification of X as 6-hydroxydopa
- 6-hydroxydopa has been implicated in neurotoxicity, the data presented suggest that this compound has a functional role at an enzyme active site
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