Radiogenomic analysis of breast cancer: dynamic contrast enhanced - magnetic resonance imaging based features are associated with molecular subtypes

We investigated associations between dynamic contrasts enhanced magnetic resonance imaging features and molecular subtypes in breast cancer

Shijian Wang

2016

Scholarcy highlights

  • Breast cancer is one of the most common malignant tumor with upgrading incidence in females
  • We investigated associations between dynamic contrasts enhanced magnetic resonance imaging features and molecular subtypes in breast cancer
  • Sixty patients with breast cancer were enrolled and the MR images were pre-processed for noise reduction, registration and segmentation
  • The associations between imaging features and molecular subtypes were assessed by using statistical analyses, including univariate logistic regression and multivariate logistic regression
  • The results of multivariate regression showed that imaging features are significantly associated with molecular subtypes of Luminal A, HER2-enriched and Basal like, respectively
  • The results indicated that three molecular subtypes are correlated with DCE-MRI features in breast cancer
  • Advanced PhotonicsJournal of Applied Remote SensingJournal of Astronomical Telescopes Instruments and SystemsJournal of Biomedical OpticsJournal of Electronic ImagingJournal of Medical ImagingJournal of Micro/Nanolithography, MEMS, and MOEMSJournal of NanophotonicsJournal of Photonics for EnergyNeurophotonicsOptical EngineeringSPIE Reviews

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