Prolonged outbreak of adenovirus A31 in allogeneic stem cell transplant recipients

We identified 9 cases of human adenovirus A31

L. Swartling


Scholarcy highlights

  • An outbreak of human adenovirus A31 occurred from December 2011 to March 2012 at the Center for Allogeneic Stem Cell Transplantation, Karolinska University Hospital in Sweden
  • The medical records of all patients admitted to CAST during the outbreak period were studied
  • Phylogenetic analysis of the patient HAdV strains was performed by sequencing the hexon gene and the more variable E3 gene
  • We identified 9 cases of HAdV A31
  • But transmission continued for 2 months
  • All 9 patients had been admitted to the ward, but 2 had no connection in time to other known HAdV A31 cases
  • Regular testing of all patients several weeks beyond the last case identified may be an important measure to control transmission

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