Topical fish oil in psoriasis-a controlled and blind study

The results showed statistically significant improvement in erythema and scaling for both treatments compared to basal values; significant differences between treatments were achieved in scaling but not in erythema

S.O. ESCOBAR

2006

Scholarcy highlights

  • Omega‐3 polyunsaturated fatty acids compete with arachidonic acid as substrates for lipoperoxidases, which transform them into leukotrienes with low biological activity
  • The results showed statistically significant improvement in erythema and scaling for both treatments compared to basal values; significant differences between treatments were achieved in scaling but not in erythema
  • Irritation and a burning sensation were reported in the fish oil treated plaque of one patient
  • This adverse effect reverted after completing the treatment. These findings demonstrate that topical FO shows a better performance than liquid paraffin under an occlusive dressing
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