The atopy patch test: an increased rate of reactivity in patients who have an air-exposed pattern of atopic eczema

This study investigates the dose-response ofthe APT in two dilTerent patient groups with AE

U. DARSOW

2008

Scholarcy highlights

  • Summary In a subgroup of patients with atopic eczema, eczematous skin lesions can he induced by epicutaneous testing with aeroallergens
  • An increased frequency of positive APT has been found in AK patients showing a predictive lesional pattern affecting air-exposed skin areas
  • This study investigates the dose-response ofthe APT in two dilTerent patient groups with AE
  • Petrolatum preparations of house dust mite, cat dander and grass pollen allergens in four concentrations were tested epicutaneously in 57 patients with AE. who were prospectively divided in two groups according to whether their AE pattern was with or without a predictive distribution
  • Sixty-nine per cent of patients in group I. and 39% in group II. had positive APT reactions
  • A clinically recognizable subgroup of patients with AE showed increased cutaneous sensitivity to aeroallergens

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