Association between vitamin D receptor polymorphisms and systemic lupus erythematosus in an Indian cohort

We investigated the association of vitamin D receptors polymorphisms with Systemic lupus erythematosus in a cohort of patients from Odisha, India

Harishankar Mahto

2017

Scholarcy highlights

  • Several studies have demonstrated an association between vitamin D receptors polymorphisms and susceptibility to Systemic lupus erythematosus in different populations, the results are still inconclusive
  • We investigated the association of VDR polymorphisms with SLE in a cohort of patients from Odisha, India
  • FokI and TaqI variants are significantly associated with SLE in an eastern Indian cohort
  • The cause-effect relationship can be assessed from the combined analyses of VDR polymorphism, plasma vitamin D levels and clinical manifestations
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