Preoperative thoracic muscle area on computed tomography predicts long-term survival following pneumonectomy for lung cancer

We investigated the relationship of the thoracic muscle with the survival of lung cancer patients who underwent pneumonectomy

Fabian M Troschel

2018

Scholarcy highlights

  • Pneumonectomy for locally advanced lung cancer still carries significant morbidity and mortality
  • Multivariable analysis showed an independent association of muscle cross-sectional area and overall survival with a hazard ratio of 0.80 per 10-cm2 increment
  • Thoracic muscle is independently associated with long-term overall survival following pneumonectomy for lung cancer and may contribute to refined survival estimates in this population
  • Muscles of all but 3 patients were completely imaged at level T8 whereas the field of view at level T5 was too small in 12 patients
  • This study adds to the findings of a recent report linking psoas muscle area to survival following pneumonectomy because our model accounts for all major confounders known to affect outcomes following lung resection
  • This study focuses on muscles that contribute to respiratory function and are included on routine preoperative chest computed tomography examinations
  • Thoracic muscle on routine preoperative chest computed tomography scans is independently associated with long-term overall survival following pneumonectomy for lung cancer

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