Contribution of environmental factors to the risk of male infertility

We found that men exposed to pesticides had higher serum oestradiol concentrations, and that men exposed to solvents had lower LH concentrations than non-exposed men

A. Oliva

2002

Scholarcy highlights

  • Humans are exposed to many environmental agents that may be hazardous to their reproductive capacity
  • Male reproductive function is known to be highly sensitive to many chemicals and physical agents generated by industrial or agricultural activities
  • This study aimed to evaluate the effect of environmental agents on seminal characteristics and reproductive hormone concentrations in the serum of male partners of infertile couples
  • We studied a population of men seeking infertility treatment, which allowed us to investigate the association between high prevalent risk factors and the outcomes related to infertility
  • If the decision to seek medical care is related to occupational exposure, this may result in increased prevalence of such factors
  • We showed that exposure to pesticides and solvents is significantly associated with threshold sperm values, much lower than the considered limits for male fertility
  • We have shown that environmental factors contribute to the severity of infertility, and that this may worsen the effects of pre-existing genetic or medical risk factors

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