Lifestyle and Demographic Factors in Relation to Vasomotor Symptoms: Baseline Results from the Study of Women's Health Across the Nation

To assess whether any associations of lifestyle factors with symptoms were due in part to hormones, we modeled each hormone as a function of each lifestyle factor using linear regression, adjusting for menstrual cycle day of blood draw

E. B. Gold; G. Block; S. Crawford; L. Lachance; G. FitzGerald; H. Miracle; S. Sherman

2004

Scholarcy highlights

  • Vasomotor symptoms affect most women during the menopausal transition, frequencies differ significantly by race/ethnicity
  • Study of Women’s Health Across the Nation showed that nutrient intakes varied considerably by race/ethnicity, with dietary antioxidant and fiber intake highest in Chinese women, phytoestrogen intake highest in Japanese women, fat and total calorie intake highest in African-American women, and any alcohol intake highest in Caucasian and lowest in Chinese women
  • The amount of cigarettes smoked, passive smoke exposure, and higher total calorie and fat intakes were significantly associated with vasomotor symptoms
  • In multivariate analyses adjusting simultaneously for ethnicity, all lifestyle factors, and confounding factors, the odds of reporting vasomotor symptoms remained significantly higher in early perimenopausal than premenopausal women and significantly higher in African-American and Hispanic women and lower in Chinese than in Caucasian women
  • The present large, multiethnic, community-based study provides new evidence that passive smoke exposure, hormones, and body mass index are associated with vasomotor symptoms in midlife women and that the reporting of these symptoms varies by race/ethnicity
  • No significant associations were found with dietary factors in this cross-sectional analysis
  • The associations found here must be further explored in longitudinal analyses, so as to help guide women and clinicians in finding lifestyle changes to prevent symptoms, reducing or providing alternatives to use of medications

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