RE: "MODELING SMOKING HISTORY: A COMPARISON OF DIFFERENT APPROACHES"
Leffondré et al did not consider a third possible approach to modeling smoking history: the use of one comprehensive smoking variable which allows for intensity, duration, and recency of smoking, including their interactions
Leffondré et al did not consider a third possible approach to modeling smoking history: the use of one comprehensive smoking variable which allows for intensity, duration, and recency of smoking, including their interactions
Such an approach would avoid the problem of multicollinearity and is promising for obtaining a good model fit
Assuming that lung cancer can be caused by a carcinogenic substance contained in cigarettes and cigarette smoke, the level of the carcinogen in the human body can partly be attributed to smoking
Am J Epidemiol 2003;158:392–395 figure 2 of Leffondré et al.’s paper, the term should be logarithmically transformed, so a comprehensive smoking variable is given by X = ln
It would be interesting to compare a lung cancer model using the proposed comprehensive smoking variable with models explored by Leffondré et al
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