Dietary calcium and vitamin D intake in elderly women: effect on serum parathyroid hormone and vitamin D metabolites

One might argue that the effect of milk calcium on the suppression of serum parathyroid hormone is mediated through increased calcium absorption because of a higher vitamin D intake, but the results show that calcium absorption in the group taking vitamin D supplements was not different from that in the group not taking supplements

H K Kinyamu; J C Gallagher; K A Rafferty; K E Balhorn

2018

Scholarcy highlights

  • Nutrition plays a role in the etiology and pathogenesis of senile osteoporosis
  • The group not taking vitamin D supplements, had a mean total calcium intake of 704 mg/d compared with an intake of 818 mg/d in the group taking vitamin D supplements
  • Because there were no significant differences between the regression slopes of serum parathyroid hormone on serum calcidiol in women taking or not taking vitamin D supplements, data were pooled for the 376 women
  • The average mean calcium intakes of 704 mg/d in women not taking vitamin D supplements and 818 mg/d in women taking vitamin D supplements were close to the recommended dietary allowance of 800 mg/d
  • As expected, vitamin D intake was greater than the RDA in women taking vitamin D supplements containing 10 ␮g/d
  • > 65 ng/L was observed in 6 of 245 of the women not taking vitamin D supplements and in 5 of 131 of the women taking vitamin D supplements; compared with young women in our laboratory, mean serum PTH increased by 30%
  • One might argue that the effect of milk calcium on the suppression of serum PTH is mediated through increased calcium absorption because of a higher vitamin D intake, but the results show that calcium absorption in the group taking vitamin D supplements was not different from that in the group not taking supplements
  • Women probably need to consume more than the current recommended dietary allowance of vitamin D to increase serum calcidiol and decrease serum parathyroid hormone to normal concentrations

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