Congenital Hypothyroidism: Etiologies, Diagnosis, and Management
An initial starting dose of 10-15 fig/kg per day is recommended; this dose will decrease on a weight basis over time
STEPHEN LaFRANCHI
2009
Scholarcy highlights
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Congenital hypothyroidism is a common preventable cause of mental retardation
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Recent mutations have been described in the genes coding for the sodium/iodide symporter, thyroid peroxidase, and thyroglobulin
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Screening test results must be confirmed by serum thyroid function tests
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Thyroid sonography is nearly as accurate, but it may miss some cases of ectopic glands
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An initial starting dose of 10-15 fig/kg per day is recommended; this dose will decrease on a weight basis over time
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1 February 2010 | BMC Endocrine Disorders, Vol 10, No 1
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