Maternal Hypothyroidism: Recognition and Management

Women with compensated early thyroid failure, or those from areas of reduced iodine intake, may first be found to be hypothyroid during pregnancy

GREGORY A. BRENT

2009

Scholarcy highlights

  • Women with compensated early thyroid failure, or those from areas of reduced iodine intake, may first be found to be hypothyroid during pregnancy
  • In women with previously diagnosed hypothyroidism already on thyroxine replacement therapy, pregnancy is often associated with an increased dose requirement
  • An increased T4 dose requirement is typically seen by the first trimester, can continue to increase throughout pregnancy, and reverts to the prepregnancy dose requirement after delivery
  • The magnitude of the increased T4 requirement is related to the etiology of hypothyroidism
  • A clinical review of obstetric and perinatal outcome in thyroid disorders

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