Surface engineering and applications of nanodiamonds in cancer treatment and imaging

Nanodiamonds are emerging as a promising platform for theranostic particles because they unite a spectrum of important properties into a single agent, including facile synthesis, small size, inertness, rich surface functional groups, biocompatibility, stable fluorescence and long fluorescence lifetime

H. Lai; M. H. Stenzel; P. Xiao

2019

Scholarcy highlights

  • Nanodiamonds are emerging as a promising platform for theranostic particles because they unite a spectrum of important properties into a single agent, including facile synthesis, small size, inertness, rich surface functional groups, biocompatibility, stable fluorescence and long fluorescence lifetime
  • These unique properties have stimulated the application of NDs in cancer treament and imaging
  • The majority of these applications rely on the rational engineering of the particle surface, as the surface plays a critical role in carrying bioactive molecules, resisting aggregation and constructing composite materials
  • A brief introduction in the structure of NDs and properties of NDs will be given, followed by a summary of various surface functionalisation methods. The latter part is organised in three subsections: NDs coated with bioactive compounds, NDs coated with synthetic polymers and NDs/inorganic composites

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