Agricultural Chemical Use and Congenital Cleft Lip and/or Palate

A case-control study utilizing vital records and ecologic, surrogate exposure measures was conducted in Iowa and Michigan

Jane E. Gordon; Carl M. Shy

2013

Scholarcy highlights

  • A case-control study utilizing vital records and ecologic, surrogate exposure measures was conducted in Iowa and Michigan
  • The major findings of these analyses suggest: an agricultural chemical effect controlling for season of conception; no independent effect of season of conception; and little chemical/season interaction. These results imply that if exposures to agricultural chemicals are, risk factors for clefts, an expanded model that accounts for multiple pesticidal exposures may be more sensitive than consideration of season of exposure, as originally hypothesized
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