A fluorometric and colorimetric dual-signal nanoplatform for ultrasensitive visual monitoring of the activity of alkaline phosphatase

For the first time, we reported a one-pot method in situ synthesis of carbon-containing nanoparticles via p-aminophenol and diethylenetriamine

Jia An; Yongqin Hu; Guoyi Liu; Meizhu Chen; Rubing Chen; Ying Lyu; Mengdi Yuan; Mengfei Luo; Yufei Liu

2021

Scholarcy highlights

  • Considering the limited sensitivity and accuracy of single-signal assay strategies, the multi-signal assay strategy has sparked significant excitement in recent years
  • For the first time, we reported a one-pot method in situ synthesis of carbon-containing nanoparticles via p-aminophenol and diethylenetriamine
  • The analytical strategy opened a new window for the detection of the alkaline phosphatase activity, screening of the ALP inhibitor, and disease diagnosis
  • A fluorometric and colorimetric dual-signal nanoplatform for ultrasensitive visual monitoring of the activity of alkaline phosphatase

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