Development of potent inhibitors for strigolactone receptor DWARF 14

We describe the development of a small-molecule DWARF 14 inhibitor that functions at sub-micromolar levels

Masahiko Yoshimura; Sojung F. Kim; Ryosuke Takise; Shuhei Kusano; Sakuya Nakamura; Masanori Izumi; Akiko Yagi; Kenichiro Itami; Shinya Hagihara

2020

Scholarcy highlights

  • Strigolactones are plant hormones that suppress shoot branching through perception by their receptor protein DWARF 14
  • The artificial regulation of SL signaling has been considered a potent agricultural technique because plant architecture is strongly related to crop yield
  • We describe the development of a small-molecule D14 inhibitor that functions at sub-micromolar levels
  • Development of potent inhibitors for strigolactone receptor DWARF 14

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