A turn-on near-infrared fluorescence probe with aggregation-induced emission based on dibenzo[a,c]phenazine for detection of superoxide anions and its application in cell imaging

A new turn-on near-infrared fluorescence probe based on dibenzo phenazine for superoxide anion detection with aggregation-induced emission properties as well as a desirable large Stokes shift was designed and synthesized

Ji Yang; Xianglong Liu; Honglei Wang; Haoqi Tan; Xiaoxu Xie; Xiao Zhang; Chenchen Liu; Xue Qu; Jianli Hua

2018

Scholarcy highlights

  • A new turn-on near-infrared fluorescence probe based on dibenzophenazine for superoxide anion detection with aggregation-induced emission properties as well as a desirable large Stokes shift was designed and synthesized
  • After BDP reacted with superoxide, the initial diphenyl-phosphinyl groups of BDP were cleaved, resulting in the production of the pyridinium modified fluorophore with near-infrared emission
  • The fluorescent sensor BDP has a high selectivity for superoxide anions over some other intracellular ROSs, reductants, metal ions and amino acids
  • A turn-on near-infrared fluorescence probe with aggregation-induced emission based on dibenzophenazine for detection of superoxide anions and its application in cell imaging

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