One pot synthesis of highly luminescent polyethylene glycol anchored carbon dots functionalized with a nuclear localization signal peptide for cell nucleus imaging

Strong blue fluorescent polyethylene glycol anchored carbon nitride dots with a high quantum yield of 75.8% have been synthesized by a one step hydrothermal treatment

Lei Yang; Weihua Jiang; Lipeng Qiu; Xuewei Jiang; Daiying Zuo; Dongkai Wang; Li Yang

2015

Scholarcy highlights

  • Strong blue fluorescent polyethylene glycol anchored carbon nitride dots with a high quantum yield of 75.8% have been synthesized by a one step hydrothermal treatment
  • Based on the as-prepared CDs, we designed novel cell nucleus targeting imaging carbon dots functionalized with a nuclear localization signal peptide
  • Intracellular localization experiments in MCF7 and A549 cells demonstrate that NLS modified CDs could be internalized in the nucleus and show blue light, which indicates that CDs may serve as cell nucleus imaging probes

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