Nucleic acid detection using carbon nanoparticles as a fluorescent sensing platform

We demonstrate for the first time the proof of concept that carbon nanoparticles can be used as an effective fluorescent sensing platform for nucleic acid detection with selectivity down to single-base mismatch

Hailong Li; Yingwei Zhang; Lei Wang; Jingqi Tian; Xuping Sun

2010

Scholarcy highlights

  • We demonstrate for the first time the proof of concept that carbon nanoparticles can be used as an effective fluorescent sensing platform for nucleic acid detection with selectivity down to single-base mismatch
  • A double-stranded DNA hybrid forms, recovering dye fluorescence

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