Graphene-based biosensors for detection of bacteria and their metabolic activities

We demonstrate a graphene based biosensor to electrically detect E. coli bacteria with high sensitivity and specificity

Yinxi Huang; Xiaochen Dong; Yuxin Liu; Lain-Jong Li; Peng Chen

2011

Scholarcy highlights

  • Graphene, which is a recently discovered single-atom-thick planar sheet of carbon atoms perfectly arranged in a honeycomb lattice, has great potential in biosensing owing to its extraordinary electrical, physical, and optical properties
  • We demonstrate a graphene based biosensor to electrically detect E. coli bacteria with high sensitivity and specificity
  • The large-sized graphene film was grown by chemical vapor deposition and functionalized with anti-E. coliantibodies and passivation layer
  • Significant conductance increase of the graphene device was observed after exposure to E. coli bacteria at a concentration as low as 10 cfu/mL, while no significant response was triggered by high concentration of the another bacterial strain
  • Graphene-based biosensors for detection of bacteria and their metabolic activities

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